Orbach Lab

“The greatest obstacle to discovery is not ignorance -
it is the illusion of knowledge ”

Daniel J. Boorstin

Research

Our lab is fascinated by self-assembly and dynamic behavior of the microtubule cytoskeleton. We are especially interested in the ciliary cytoskeleton, known as the axoneme. Using cutting-edge microscopy techniques, advanced biochemistry, quantitative image analysis and various multidisciplinary approaches we aim to answer basic questions related to the cilia.

Mohammed Passed His Qualifying Exam

Congratulations to Mohammed for successfully passing his qualifying exam! His hard work and dedication have paid off, and now he is ready...

Microtubule Meeting 2024

Every other year, the European Molecular Biology Laboratory (EMBL) hosts a prestigious microtubule meeting, bringing together leading...

Grant News

The lab was awarded a research grant by the David and Fela Shapell Family Center for Genetic Disorders Research. We thank the reviewers...

Highlighted Publication

The Dynamic and Structural Properties of Axonemal Tubulins Support the High Length Stability of Cilia

The work describes a novel biochemical assay to purify axonemal tubulins from the central pair and the doublets. Using in vitro work, we characterize two distinct mechanisms that enable tubulins to support the length stability of the axoneme.

Orbach Lab

Research

News & Events

Highlighted Publication